Vitamin B12 Showdown: Cyanocobalamin vs. Methylcobalamin! When it comes to Vitamin B12, not all forms are created equal! Let's break down the key differences between the two most popular types Cyanocobalamin vs Hydroxocobalamin (Vitamin B12 forms) Key Clinical Differences Hydroxocobalamin is preferred in: Pernicious anemia Severe vitamin B12 deficiency Neurological symptoms (subacute combined degeneration, neuropathy) Cyanocobalamin is Do You Need a Prescription for B12 Injections? OmegaQuant What is the appropriate dosing schedule for vitamin B12 (cyanocobalamin or methylcobalamin) injections in a patient with a confirmed deficiency?